The project’s objective is to develop the research and development infrastructure ofbacteriology, biochemistry, immunology, hematology and genetics laboratories from IOMC. Under the infrastructure, the priority is on the research activity in the field of rare diseases in children, field which currently is not properly and at European standards approached in our country. The project aims at a complex multidisciplinary approach in the field of rare diseases, thus bringing new knowledge about epidemiology, diagnosis, treatment and assessment of therapeutical efficiency regarding these diseases.